Cross-consortium Use Cases

Beyond the boundaries of the consortia

Collaboration for improved regional patient care

In addition to the use cases of the four consortia, the participants in the Medical Informatics Initiative (MII) are also working on clinical and methodological use cases across consortia. The aim is to show how the data of the data integration centers at the university medical sites can be used together for improved medical research and more individualized patient care. The cross-consortium use cases always address current medical requirements. Currently, projects are being performed in the areas of rare diseases (CORD_MI), biobanks (ABIDE_MI) and polymedication (POLAR_MI).


The aim of the project “Aligning Biobanking and DIC Efficiently” (ABIDE_MI), which started in May 2021, is to link patient data obtained under the Medical Informatics Initiative (MII) with data from biospecimens and make them usable for research. With the German Portal for Medical Research Data (GPRM), the MII, the German Biobank Node (GBN) and the biobanks of the German Biobank Alliance (GBA) are contributing to a sustainable health IT infrastructure. In the future, researchers will be able to submit feasibility queries via this portal. For this purpose, ABIDE is developing the technical and regulatory framework for cooperation between biobanks and DIC at 24 German university medicine sites.

Find further information on ABIDE-MI here.

Use Case CORD_MI

The Collaboration on Rare Diseases (CORD-MI) use case aims to improve care and research in the field of rare diseases. The project builds on other innovation fund projects that support the coding of rare diseases and create better care structures for patients. Concepts and solutions are developed to improve the documentation of rare diseases in university hospitals and to make the data obtained jointly usable. The data can help to better recognize and classify rare diseases. This, in turn, makes it possible for affected individuals to access appropriate treatment more quickly. In the long term, CORD-MI aims to establish sustainable structures for a digital network to exchange data on rare diseases.

Find further information on CORD-MI here.


The use case “POLypharmacy, drug interactions and risks” (POLAR_MI) is intended to contribute to the detection of health risks in patients with polymedication. Older people in particular often take many different medications. This can lead to undesirable side effects and drug interactions that trigger additional disease patterns and the need for therapy. The POLAR use case is designed to help predict potentially inadequate medications and associated risks by collecting data on commonly prescribed medications. In this way, patients who are at high risk for adverse drug effects can be identified. This makes it possible to specifically analyse and prevent undesirable health consequences that can result from adverse drug effects. POLAR thus contributes to better drug management.

Find further information on POLAR_MI here.