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Semantic interoperability in the SMITH Consortium with FHIR and SNOMED CT

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In order to optimally process and use medical data for patient care and clinical research, it is important to establish semantic interoperability. This means describing data with globally unique codes, such as those found in the comprehensive ontology SNOMED CT. But how can such semantic annotations be made? In this article we will show you how this work is done in the data integration centers of the SMITH Consortium based on the HL7 standard FHIR!

SMITH is a research project funded by the Medical Informatics Initiative of the German Federal Ministry of Education and Research (BMBF) and focuses on the establishment and networking of data integration centers at the participating university medical sites.



Danny Ammon
Jena University Hospital
Data Integration Center
Stoystraße 3
07743 Jena

Dr. Danny Ammon studied computer science and earned his doctorate in medical informatics at Technische Universität Ilmenau. After working in and coordinating research projects in the areas of clinical process management, telemedicine and medical decision support, he has been leading the Data Integration Center at the IT Department of Jena University Hospital since 2018.


André Sander
ID GmbH & Co. KGaA
Platz vor dem Neuen Tor 2
10115 Berlin

You can find the resume of André Sander here.


Thomas Nitzsche
InterSystems GmbH
Robert-Bosch-Straße 16a
64293 Darmstadt

Thomas Nitzsche is a Sales Engineer at InterSystems. His main topics are the development of platforms for healthcare networks and the processing of structured and unstructured data. Furthermore, he is doing his PhD at the Faculty of Medicine at the Leipzig University on the topic of standardized communication architecture in the area of Ambient Assisted Living. Before joining InterSystems in 2013, he studied computer science at the Westsächsische Hochschule Zwickau with a focus on medical informatics and was subsequently a research assistant there. In addition, he worked for various healthcare institutions and associations as well as for IT manufacturers in the healthcare sector. He is an active member in GMDS, BVMI and VDE.


Matthias Löbe
Leipzig University, IMISE
Härtelstraße 16–18
04107 Leipzig

Matthias Löbe has been working as a research associate at the Institute for Medical Informatics, Statistics and Epidemiology (IMISE) of the Leipzig University since 2002. In the SMITH Project, he leads the subproject on semantic interoperability. Within the Medical Informatics Initiative he is mainly working on the Core Data Set. His research areas are clinical data models/interoperability, research data management/FAIR data, metadata and terminologies.